Tag: Proteolysis targeting chimera

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Recent Related Articles to Proteolysis targeting chimera

Monte Rosa snags $95M to speed lead 'molecular glue' treatment into the clinic

Added to Collection on: 2021-03-12 15:24:45

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Branches of biology
Biology
Transcription factors
Proteins
Gene expression
N-Myc
Myc
Proteasome
Druggability
Proteolysis targeting chimera
Ubiquitin
Monte Rosa
Markus Warmuth

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A Quick and Efficient Strategy for Affinity Screening | The Scientist Magazine®

Added to Collection on: 2023-12-11 20:55:30

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Biotechnology
Pharmacology
Proteolysis targeting chimera
Assay
Druggability

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ASU researcher awarded $1.25M to develop programmable, targeted drugs

Added to Collection on: 2024-07-26 21:59:15

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Biotechnology
Chemical biology
Pharmacology
Proteolysis targeting chimera
Molecular biology
DNA nanotechnology
Protein
Proteolysis
Craig M. Crews
Molecular glue
Hao Yan

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Targeted protein degradation using chimeric human E2 ubiquitin-conjugating enzymes

Added to Collection on: 2024-09-19 22:26:27

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Posttranslational modification
Proteins
Tyrosine kinase receptors
Ubiquitin ligase
PTPN11
Hepatocyte growth factor receptor
Von Hippel–Lindau tumor suppressor
Ubiquitin
Proteolysis targeting chimera
Proteasome
Ras GTPase
Small interfering RNA

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NiKang concludes first cohort dosing in Phase I trial of NKT3964 for tumours

Added to Collection on: 2025-03-11 17:59:04

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Proteins
Cell cycle
Cyclin-dependent kinase
Cyclin E
Proteolysis targeting chimera

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Why molecular glue degraders are emerging as a key modality in drug discovery

Added to Collection on: 2025-03-31 22:26:13

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Biotechnology
Medicinal chemistry
Proteins
Protein complexes
Molecular glue
Proteolysis targeting chimera
Proteasome
Ubiquitin
Protein?protein interaction
Druggability
Craig M. Crews
Daniel Nomura
Benedict Cross

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What makes PROTACs and MGDs game-changers in drug discovery?

Added to Collection on: 2025-09-15 19:16:56

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Biotechnology
Proteins
Posttranslational modification
Chemical biology
Pharmacology
Proteolysis targeting chimera
Molecular glue
Ubiquitin ligase
Luxdegalutamide
Cereblon
Von Hippel–Lindau tumor suppressor
Proteasome
Sino Biological Inc

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Arvinas reboots, cuts more staff; Porges joins Lazard - BioPharma Dive

Added to Collection on: 2025-09-19 15:30:26

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Rare diseases
GLP-1 receptor agonists
PEPTIDE THERAPEUTICS
Garetosmab
Vertex Pharmaceuticals
Thalassemia
Regeneron Pharmaceuticals
Proteolysis targeting chimera
Sickle-cell disease
Novo Nordisk
Pfizer
Fibrodysplasia ossificans progressiva
United States

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High-throughput proteomics is identifying molecular glue degraders at scale - Nature

Added to Collection on: 2025-10-01 19:10:48

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Biotechnology
Medicinal chemistry
Proteomics
Chemical biology
Omics
Molecular glue
Interactome
Proteolysis targeting chimera
Proteome
Ubiquitin ligase
Drug discovery
Chimeric small molecule therapeutics

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