Could Antibody-Based Interventions Hold The Key To Tackling The World's Deadliest ...

A study led by Dr. Azza Idris and Dr. Galit Alter from the Ragon Institute explores engineering antibodies to provide complete protection against malaria by preventing infection altogether.

The research focuses on enhancing antibody-based solutions to combat the global health threat posed by malaria, particularly in the African region where access to prevention and treatment services is limited. Modified antibodies demonstrated increased protection by enhancing immune responses, potentially reducing dosages and increasing accessibility.

• Malaria remains a global health challenge, especially in Africa.
• Antibody engineering shows promise in preventing malaria infection.
• Modified antibodies CIS43LS-DE and CIS43LS-DEAL showed high protection rates.
• Efforts aim to boost antibody potency and accessibility while managing costs.